Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730595 | 0.88 | TACR1 (0.58) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729849 | 0.88 | TACR1 (0.58) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729860 | 0.83 | MEN1 (0.53) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9730103 | 0.83 | MAPT (0.56) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729230 | 0.82 | MEN1 (0.52) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729926 | 0.81 | TACR1 (0.55) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729215 | 0.81 | TACR1 (0.51) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9730176 | 0.81 | TACR1 (0.53) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9730167 | 0.81 | MEN1 (0.51) | TACR1CYP2C19MAPTMEN1CYP3A4 | |
| SCHEMBL9729456 | 0.80 | TACR1 (0.59) | TACR1CYP2C19MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |