Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9730818 | 0.94 | MAPT (0.49) | HSD17B10LMNAMAPTICMTGMNN | |
| SCHEMBL10639923 | 0.84 | LMNA (0.48) | LMNAMAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10639930 | 0.84 | LMNA (0.48) | LMNAMAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5144242 | 0.80 | LMNA (0.44) | LMNACYP1A2CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5144238 | 0.80 | LMNA (0.44) | LMNACYP1A2CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL9730370 | 0.79 | LMNA (0.54) | LMNAMAPTPOLBTSHRALDH1A1 | |
| SCHEMBL9729574 | 0.77 | PDPK1 (0.39) | HSD17B10LMNAMAPTICMTGMNN | |
| SCHEMBL9671197 | 0.74 | PDE7A (0.59) | TSHRALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL9671209 | 0.74 | PDE7A (0.59) | TSHRALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10636971 | 0.74 | LMNA (0.46) | LMNAMAPTTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |