Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084121 | 0.89 | LMNA (0.62) | LMNAKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL10639923 | 0.84 | LMNA (0.48) | LMNAALDH1A1TNFTSHRSMN1; SMN2 | |
| SCHEMBL10639930 | 0.84 | LMNA (0.48) | LMNAALDH1A1TNFTSHRSMN1; SMN2 | |
| SCHEMBL5144238 | 0.83 | LMNA (0.44) | LMNAKMT2AALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL5144242 | 0.83 | LMNA (0.44) | LMNAKMT2AALDH1A1ALDH1A2ALDH2 | |
| SCHEMBL9729392 | 0.79 | HSD17B10 (0.46) | LMNAKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL1520132 | 0.75 | PKM (0.67) | LMNAKMT2AKDM4EPOLBALDH1A1 | |
| Oxalic Acid SCHEMBL9730818 | 0.75 | MAPT (0.49) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9730248 | 0.75 | MAPT (0.43) | LMNAKMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL10639415 | 0.74 | KDM4E (0.46) | LMNAKMT2AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |