Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730061 | 0.90 | NAPRT (0.47) | NPSR1KMT2AALDH1A1LMNANAPRT | |
| SCHEMBL9729603 | 0.73 | LMNA (0.52) | KMT2AALDH1A1LMNANAPRTP2RX7 | |
| SCHEMBL9730160 | 0.73 | IDO1 (0.44) | KMT2AALDH1A1LMNANAPRTCYP1A2 | |
| SCHEMBL9323795 | 0.72 | NAPRT (0.54) | KMT2ALMNANAPRTCYP1A2CYP3A4 | |
| SCHEMBL9323799 | 0.72 | NAPRT (0.54) | KMT2ALMNANAPRTCYP1A2CYP3A4 | |
| SCHEMBL9729510 | 0.70 | NAPRT (0.37) | NPSR1ALDH1A1LMNANAPRTCYP1A2 | |
| SCHEMBL9730751 | 0.69 | NAPRT (0.35) | ALDH1A1LMNANAPRTCYP1A2CYP3A4 | |
| SCHEMBL5634650 | 0.66 | NAPRT (0.55) | ALDH1A1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10744051 | 0.66 | NAPRT (0.55) | KMT2AALDH1A1L3MBTL1NAPRTCYP1A2 | |
| SCHEMBL3524143 | 0.66 | NAPRT (0.55) | ALDH1A1NAPRTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |