Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323795 | 1.00 | NAPRT (0.54) | NAPRTKEAP1KMT2ALMNATDP1 | |
| SCHEMBL10666387 | 0.90 | KMT2A (0.51) | NAPRTKEAP1KMT2ALMNATDP1 | |
| SCHEMBL7365545 | 0.84 | TBXAS1 (0.49) | KEAP1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL7365547 | 0.84 | TBXAS1 (0.49) | KEAP1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL257218 | 0.82 | CTSL (0.55) | KDM4ESMN1; SMN2 | |
| SCHEMBL4586154 | 0.82 | CTSL (0.55) | KDM4ESMN1; SMN2 | |
| SCHEMBL4586157 | 0.82 | CTSL (0.55) | KDM4ESMN1; SMN2 | |
| SCHEMBL9324776 | 0.81 | KDM4E (0.46) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9321485 | 0.81 | GAA (0.50) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9324768 | 0.81 | KDM4E (0.46) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278090-B1 | 2-Aminoacetamide pyridinyl derivatives | FISONS CORP (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| US-4769466-A | 2-aminoacetamide pyridinyl derivatives | PENNWALT CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |