Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202121 | 0.78 | SMPD1 (0.37) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL7006858 | 0.72 | SMPD1 (0.41) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL5982297 | 0.70 | SMPD1 (0.32) | SMPD1 | |
| SCHEMBL10422584 | 0.70 | SMPD1 (0.32) | SMPD1 | |
| SCHEMBL5909138 | 0.69 | SMPD1 (0.43) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL433467 | 0.69 | SMPD1 (0.43) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL9750400 | 0.67 | SMPD1 (0.47) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL98484 | 0.67 | LMNA (0.39) | LPAR3LPAR1 | |
| SCHEMBL202465 | 0.67 | SMPD1 (0.47) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL1921756 | 0.67 | SMPD1 (0.42) | SMPD1LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079245-A | 2-trifluoromethyl-7-substitute-6,7,8,9-tetrahydro-[5H]-benzocycloheptenes | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |