Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26135756 | 0.76 | FDPS (0.39) | SMPD1FDPS | |
| SCHEMBL9729488 | 0.70 | SMPD1 (0.37) | SMPD1 | |
| SCHEMBL3902815 | 0.70 | — | — | |
| SCHEMBL3202121 | 0.70 | SMPD1 (0.37) | SMPD1 | |
| SCHEMBL28729195 | 0.69 | LMNA (0.40) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL27570533 | 0.69 | LMNA (0.40) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL5963785 | 0.69 | LMNA (0.40) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL332472 | 0.69 | — | — | |
| SCHEMBL5400918 | 0.67 | LMNA (0.38) | SMPD1LMNAFDPSBLMTDP1 | |
| Ammonia Solution, Strong SCHEMBL1310966 | 0.67 | LMNA (0.38) | SMPD1LMNAFDPSBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644394-A2 | SYNTHESIS AND COMPOSITIONS OF 2 -TERMINATOR NUCLEOTIDES | Roche Diagnostics GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005026184-A9 | SYNTHESIS AND COMPOSITIONS OF 2'-TERMINATOR NUCLEOTIDES | ROCHE DIAGNOSTICS GMBH (DE) | 2006-03-02 | — | — | WO | disclosed |
| WO-2005026184-A2 | SYNTHESIS AND COMPOSITIONS OF 2'-TERMINATOR NUCLEOTIDES | ROCHE DIAGNOSTICS GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |