Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730614 | 0.82 | KMT2A (0.43) | KMT2ARAB9AALDH1A1MEN1NPC1 | |
| SCHEMBL10906811 | 0.78 | POLB (0.47) | KMT2ARAB9AALDH1A1MEN1NPC1 | |
| SCHEMBL7269217 | 0.76 | POLB (0.47) | KMT2AALDH1A1MAPTCYP11B2CYP19A1 | |
| SCHEMBL11244188 | 0.74 | RAB9A (0.52) | KMT2ARAB9AALDH1A1MEN1NPC1 | |
| SCHEMBL9729380 | 0.74 | RAB9A (0.42) | KMT2ARAB9AALDH1A1MEN1NPC1 | |
| SCHEMBL9372025 | 0.73 | SMN1; SMN2 (0.41) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL9877764 | 0.73 | ALDH1A1 (0.51) | KMT2ARAB9AALDH1A1MEN1NPC1 | |
| SCHEMBL4418464 | 0.73 | CYP19A1 (0.54) | LMNACYP19A1GAA | |
| SCHEMBL27492286 | 0.72 | CYP19A1 (0.52) | LMNACYP19A1GAA | |
| SCHEMBL30209768 | 0.72 | SMN1; SMN2 (0.59) | KMT2ARAB9AALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0445069-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |