Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TACR1 | P25103 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730595 | 0.87 | TACR1 (0.58) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9729849 | 0.87 | TACR1 (0.58) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9730167 | 0.85 | MEN1 (0.51) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9730176 | 0.85 | TACR1 (0.53) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9730103 | 0.82 | MAPT (0.56) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9729197 | 0.82 | TACR1 (0.55) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9729490 | 0.82 | TACR1 (0.48) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9730126 | 0.82 | TACR1 (0.51) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9729860 | 0.80 | MEN1 (0.53) | KMT2AMEN1TACR1MAPTCYP3A4 | |
| SCHEMBL9729215 | 0.80 | TACR1 (0.51) | KMT2AMEN1TACR1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |