Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730126 | 0.94 | TACR1 (0.51) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729849 | 0.90 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730595 | 0.90 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730167 | 0.88 | MEN1 (0.51) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729512 | 0.85 | KMT2A (0.50) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729490 | 0.84 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730188 | 0.84 | MAPT (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730103 | 0.82 | MAPT (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729234 | 0.82 | TACR1 (0.61) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729860 | 0.82 | MEN1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |