Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019081 | 0.86 | MEN1 (0.53) | TSHRMAPK1MAOBMAOAMEN1 | |
| SCHEMBL11020635 | 0.86 | MEN1 (0.53) | TSHRMAPK1MAOBMAOAMEN1 | |
| SCHEMBL11023346 | 0.86 | MEN1 (0.53) | TSHRMAPK1MAOBMAOAMEN1 | |
| SCHEMBL14880514 | 0.81 | MAOB (0.58) | MAOBMAOAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9591612 | 0.80 | TDP1 (0.56) | TSHRTDP1ALDH1A1NPC1MAPT | |
| SCHEMBL11020247 | 0.76 | KMT2A (0.60) | NPBWR1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL29395323 | 0.75 | NPBWR1 (0.52) | TSHRMAPK1NPBWR1TDP1ALDH1A1 | |
| SCHEMBL439935 | 0.74 | APP (0.64) | TSHRALDH1A1NPC1LMNAMAPT | |
| SCHEMBL9592335 | 0.74 | TDP1 (0.48) | TDP1ALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL3366106 | 0.73 | MAOB (0.68) | MAOBMAOAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |