SCHEMBL11020635

SCHEMBL11020635

O=[N+]([O-])c1ccc(/C=C/c2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
NPC1 O15118 2/20 0.53
MAPT P10636 2/20 0.53
RAB9A P51151 2/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PTGS2 P35354 5/20 0.51
PTGS1 P23219 2/20 0.51
CYP19A1 P11511 2/20 0.51
MAOB P27338 3/20 0.51
MAOA P21397 1/20 0.51
POLB P06746 1/20 0.51
APP P05067 1/20 0.50
FBP1 P09467 1/20 0.49
TLR9 Q9NR96 1/20 0.48
KDM4A O75164 1/20 0.47
KDM4B O94953 1/20 0.47
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11019081 1.00 MEN1 (0.53) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL11023346 1.00 MEN1 (0.53) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL11020247 0.91 KMT2A (0.60) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL9729547 0.86 TSHR (0.47) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL7110533 0.84 NFE2L2 (0.60) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL7994558 0.84 NFE2L2 (0.60) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL7110537 0.84 NFE2L2 (0.60) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL3366102 0.83 MAOB (0.68) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL3366106 0.83 MAOB (0.68) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL8618370 0.83 MAOB (0.68) MEN1KMT2ANPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159587-A2 N-Benzoyl-, N'-stilbeneureas, process for their preparation and their use for pest control BASF Aktiengesellschaft (DE) 1985-10-30 EP disclosed