Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729255 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2GAALMNATAAR1ALDH1A1 | |
| SCHEMBL838467 | 0.81 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNAALDH1A1POLBNPC1 | |
| SCHEMBL7638563 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAALDH1A1POLBNPC1 | |
| SCHEMBL4532658 | 0.79 | MAPT (0.58) | SMN1; SMN2GAATAAR1ALDH1A1POLB | |
| SCHEMBL7962013 | 0.76 | GAA (0.50) | SMN1; SMN2GAATAAR1ALDH1A1POLB | |
| SCHEMBL12851348 | 0.75 | TP53 (0.67) | SMN1; SMN2LMNAALDH1A1POLBNPC1 | |
| SCHEMBL8489211 | 0.74 | TAAR1 (0.55) | SMN1; SMN2GAATAAR1ALDH1A1KMT2A | |
| SCHEMBL14814503 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2GAALMNAALDH1A1POLB | |
| SCHEMBL29570152 | 0.73 | AKR1B1 (0.74) | SMN1; SMN2GAATAAR1ALDH1A1NPC1 | |
| SCHEMBL1285811 | 0.73 | AKR1B1 (0.74) | SMN1; SMN2GAATAAR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |