Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729592 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AGAALMNAALDH1A1 | |
| SCHEMBL9473172 | 0.78 | GAA (0.41) | SMN1; SMN2KMT2AMAPK8GAAALDH1A1 | |
| SCHEMBL9985451 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AMAPK8GAA | |
| SCHEMBL7633816 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AMAPK8LMNA | |
| SCHEMBL27924459 | 0.74 | MAPK8 (0.41) | SMN1; SMN2KMT2AMAPK8GAAALDH1A1 | |
| SCHEMBL1461227 | 0.74 | CES2 (0.44) | SMN1; SMN2KMT2AMAPK8GAAALDH1A1 | |
| SCHEMBL15777690 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AMAPK8LMNA | |
| SCHEMBL28031637 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL7374522 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AMAPK8LMNA | |
| SCHEMBL9734281 | 0.69 | TP53 (0.54) | SMN1; SMN2MAPK8GAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |