Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088907 | 0.88 | ALOX5 (0.40) | ALOX5CA12CA9KDM4EGAA | |
| SCHEMBL2568148 | 0.79 | PTGS1 (0.51) | ALOX5MAOBKDM4EGAANPC1 | |
| SCHEMBL29804937 | 0.79 | PTGS1 (0.51) | ALOX5MAOBKDM4EGAANPC1 | |
| SCHEMBL9729708 | 0.78 | ALOX5 (0.54) | ALOX5MAOBPTGS2PTGS1 | |
| SCHEMBL9157430 | 0.78 | ALOX5 (0.48) | ALOX5MAOBKDM4EGAANPC1 | |
| SCHEMBL9157439 | 0.78 | ALOX5 (0.48) | ALOX5MAOBKDM4EGAANPC1 | |
| SCHEMBL9729807 | 0.76 | MAOB (0.52) | ALOX5CA12CA9MAOBMAPT | |
| SCHEMBL8626959 | 0.76 | MEN1 (0.49) | CA12CA9MAOBKDM4EGAA | |
| SCHEMBL1079406 | 0.76 | MAPT (0.42) | CA12CA9MAOBKDM4EGAA | |
| SCHEMBL3608669 | 0.76 | MAOB (0.47) | ALOX5MAOBKDM4EMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |