Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPR1 | P16066 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542237 | 0.82 | MAOB (0.53) | MAOBALOX5PTGS1PTGS2TP53 | |
| SCHEMBL8542232 | 0.82 | MAOB (0.53) | MAOBALOX5PTGS1PTGS2TP53 | |
| SCHEMBL1079406 | 0.80 | MAPT (0.42) | MAOBPTGS1PTGS2MAPTAPP | |
| SCHEMBL8626959 | 0.80 | MEN1 (0.49) | MAOBPTGS1PTGS2TP53MAPT | |
| SCHEMBL31191990 | 0.76 | CA12 (0.40) | MAOBPTGS1PTGS2MAPTAPP | |
| SCHEMBL28002706 | 0.76 | PTGS2 (0.47) | MAOBALOX5PTGS1PTGS2MAPT | |
| SCHEMBL8627404 | 0.76 | MAOB (0.57) | MAOBALOX5PTGS1PTGS2TP53 | |
| SCHEMBL9729620 | 0.76 | ALOX5 (0.51) | MAOBALOX5PTGS1PTGS2MAPT | |
| SCHEMBL29804937 | 0.75 | PTGS1 (0.51) | MAOBALOX5PTGS1PTGS2MAPT | |
| SCHEMBL2568148 | 0.75 | PTGS1 (0.51) | MAOBALOX5PTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |