Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672650 | 0.84 | MEN1 (0.50) | MEN1KMT2ACYP2C9HDAC4HSD11B1 | |
| SCHEMBL16091019 | 0.84 | MEN1 (0.50) | MEN1KMT2ACYP2C9HDAC4HSD11B1 | |
| SCHEMBL17982791 | 0.81 | MEN1 (0.41) | MEN1KMT2ACYP2C9HDAC4PSEN1 | |
| SCHEMBL6952827 | 0.81 | OPRM1 (0.50) | MEN1KMT2ACYP2C9HDAC4PSEN1 | |
| SCHEMBL14672582 | 0.80 | MEN1 (0.46) | MEN1KMT2ACYP2C9OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL5766867 | 0.79 | MEN1 (0.40) | MEN1KMT2ACYP2C9HDAC4PSEN1 | |
| SCHEMBL30666454 | 0.79 | KMT2A (0.57) | MEN1KMT2ACYP2C9GAARECQL | |
| SCHEMBL5894829 | 0.79 | KMT2A (0.57) | MEN1KMT2ACYP2C9GAARECQL | |
| SCHEMBL1557008 | 0.78 | MEN1 (0.39) | MEN1KMT2ACYP2C9HDAC4PSEN1 | |
| SCHEMBL2830652 | 0.78 | CYP2C9 (0.39) | MEN1KMT2ACYP2C9HDAC4PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |