Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067218 | 0.82 | MEN1 (0.43) | MEN1CYP2C9KMT2AKDM1AHSD11B1 | |
| Hydrochloric Acid SCHEMBL5766458 | 0.81 | KDM1A (0.45) | MEN1CYP2C9KMT2AKDM1ASLC6A4 | |
| SCHEMBL11702985 | 0.80 | PDE4A (0.43) | MEN1CYP2C9KMT2AKDM1AHSD11B1 | |
| SCHEMBL517439 | 0.80 | OPRL1 (0.50) | KDM1ASLC6A4SLC6A3SLC6A2OPRM1 | |
| SCHEMBL8767025 | 0.79 | SLC6A4 (0.56) | KDM1AHSD11B1HSD11B2SLC6A4SLC6A3 | |
| SCHEMBL5768673 | 0.78 | AKR1C1 (0.46) | MEN1CYP2C9KMT2AKDM1AHSD11B1 | |
| SCHEMBL22423724 | 0.78 | PDE4A (0.44) | MEN1CYP2C9KMT2AKDM1AHSD11B1 | |
| SCHEMBL1556970 | 0.78 | ALDH1A1 (0.45) | MEN1CYP2C9KMT2AKDM1ASLC6A4 | |
| SCHEMBL9729268 | 0.78 | MEN1 (0.60) | MEN1CYP2C9KMT2AHSD11B1SLC6A4 | |
| SCHEMBL9729492 | 0.78 | MEN1 (0.60) | MEN1CYP2C9KMT2AHSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |