Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.37 |
| ▸ | CHRNG | P07510 | 2/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796632 | 0.82 | KCNA3 (0.48) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL11095398 | 0.80 | SLC6A3 (0.47) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL11094391 | 0.78 | KCNA3 (0.51) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL4429705 | 0.78 | PDE4A (0.44) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL11092837 | 0.78 | SLC6A4 (0.46) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL11802151 | 0.78 | ALOX5 (0.52) | MEN1KMT2ACYP2C9KCNA3SLC6A3 | |
| SCHEMBL9729638 | 0.78 | MEN1 (0.60) | MEN1KMT2ACYP2C9SLC6A3SLC6A4 | |
| SCHEMBL9729492 | 0.78 | MEN1 (0.60) | MEN1KMT2ACYP2C9SLC6A3SLC6A2 | |
| SCHEMBL8121636 | 0.78 | SLC6A4 (0.40) | MEN1KMT2AKCNA3SLC6A3SLC6A4 | |
| SCHEMBL11095896 | 0.76 | KCNA3 (0.41) | MEN1KMT2ACYP2C9KCNA3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |