Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730595 | 0.85 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729849 | 0.85 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729733 | 0.82 | TACR1 (0.47) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729215 | 0.82 | TACR1 (0.51) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729456 | 0.81 | TACR1 (0.59) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730103 | 0.80 | MAPT (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730227 | 0.80 | TACR1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729985 | 0.80 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729329 | 0.80 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730246 | 0.80 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |