Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838325 | 0.81 | EPHX1 (0.40) | L3MBTL1HTTSMN1; SMN2NPC1 | |
| SCHEMBL5042530 | 0.79 | HTT (0.43) | HCRTR2HCRTR1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL11608320 | 0.75 | EPHX1 (0.42) | L3MBTL1HTTSMN1; SMN2NPC1 | |
| SCHEMBL9729470 | 0.74 | ALDH1A1 (0.47) | HCRTR2HCRTR1TMEM97SIGMAR1TBXA2R | |
| SCHEMBL2038232 | 0.74 | HCRTR2 (0.39) | HCRTR2HCRTR1L3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL1030224 | 0.74 | HCRTR2 (0.39) | HCRTR2HCRTR1L3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL1030223 | 0.74 | HCRTR2 (0.39) | HCRTR2HCRTR1L3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL13446994 | 0.74 | ALDH1A1 (0.49) | L3MBTL1HTT | |
| SCHEMBL11617650 | 0.73 | ALDH1A1 (0.49) | TMEM97SIGMAR1GAA | |
| SCHEMBL8413516 | 0.73 | TSHR (0.55) | L3MBTL1TMEM97SIGMAR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110957-A | PROCESS FOR PREPARING 1,3-DIOXOLANE KETONES | SHELL RESEARCH LIMITED (GB) | 1992-05-05 | — | — | US | disclosed |