SCHEMBL9729470

SCHEMBL9729470

CC1(C)OC[C@@H](C(=O)CCc2ccccc2)O1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TMEM97 Q5BJF2 2/20 0.46
SIGMAR1 Q99720 2/20 0.46
KEAP1 Q14145 1/20 0.42
TBXA2R P21731 1/20 0.41
FFAR1 O14842 1/20 0.40
HCRTR2 O43614 2/20 0.40
HCRTR1 O43613 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8410430 0.76 TSHR (0.55) ALDH1A1TMEM97SIGMAR1
SCHEMBL8410423 0.76 TSHR (0.55) ALDH1A1TMEM97SIGMAR1
SCHEMBL8413516 0.76 TSHR (0.55) ALDH1A1TMEM97SIGMAR1
SCHEMBL31047712 0.76 ALDH1A1 (0.49) ALDH1A1TMEM97SIGMAR1
SCHEMBL11617650 0.76 ALDH1A1 (0.49) ALDH1A1TMEM97SIGMAR1
SCHEMBL9730141 0.74 HCRTR2 (0.44) TMEM97SIGMAR1TBXA2RHCRTR2HCRTR1
SCHEMBL21416562 0.74 ALDH1A1 (0.46) ALDH1A1TMEM97SIGMAR1TBXA2R
SCHEMBL7436508 0.74 ALDH1A1 (0.46) ALDH1A1KEAP1FFAR1
SCHEMBL15325126 0.72 ALDH1A1 (0.45) ALDH1A1KEAP1FFAR1
SCHEMBL15326310 0.72 ALDH1A1 (0.45) ALDH1A1KEAP1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110957-A PROCESS FOR PREPARING 1,3-DIOXOLANE KETONES SHELL RESEARCH LIMITED (GB) 1992-05-05 US disclosed
EP-0413401-A2 Process for preparing 1,3-dioxolane ketones SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-02-20 EP disclosed