Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12937772 | 0.94 | ACE2 (0.53) | ACE2MAPTGPR84FFAR1CA1 | |
| SCHEMBL18270562 | 0.94 | ACE2 (0.53) | ACE2MAPTGPR84FFAR1CA1 | |
| SCHEMBL6427506 | 0.94 | ACE2 (0.53) | ACE2MAPTGPR84FFAR1CA1 | |
| SCHEMBL9899968 | 0.89 | ACE2 (0.56) | ACE2CES2MAPTGPR84FFAR1 | |
| SCHEMBL6426463 | 0.86 | ACE2 (0.53) | ACE2MAPTGPR84CA1GABRR1 | |
| SCHEMBL2230658 | 0.82 | ACE2 (0.48) | ACE2GPR84CA1GABRR1CYP1A2 | |
| SCHEMBL11844397 | 0.82 | USP2 (0.48) | ACE2CES2HTTPLA2G2CCYP1A2 | |
| SCHEMBL3349425 | 0.81 | CES2 (0.50) | CES2MAPTMEN1THRBHTT | |
| SCHEMBL14516298 | 0.81 | GABRR1 (0.42) | ACE2MAPTMEN1THRBHTT | |
| Lactic Acid SCHEMBL27991357 | 0.80 | CES2 (0.53) | ACE2CES2MAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461835-A | RESOLVING ARYLOXY-A-ALKYL ESTERS TO MAKE VITAMIN E INTERMEDIATES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1984-07-24 | — | — | US | claimed |
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |