Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446836 | 0.94 | ACE2 (0.46) | USP2ACE2LPAR1LPAR3PLA2G2C | |
| SCHEMBL16299711 | 0.94 | ACE2 (0.46) | USP2ACE2LPAR1LPAR3PLA2G2C | |
| SCHEMBL3283814 | 0.85 | HSD17B10 (0.54) | USP2ACE2HTTCYP1A2CYP3A4 | |
| SCHEMBL28421813 | 0.82 | CES2 (0.55) | USP2LPAR1LPAR3PLA2G2CSPHK1 | |
| SCHEMBL16467140 | 0.82 | USP2 (0.47) | USP2LPAR1LPAR3PLA2G2CSPHK1 | |
| SCHEMBL9730273 | 0.82 | ACE2 (0.56) | ACE2PLA2G2CHTTCES2CYP1A2 | |
| SCHEMBL21896392 | 0.81 | PAOX (0.42) | USP2ACE2LPAR1LPAR3PLA2G2C | |
| SCHEMBL10948512 | 0.81 | PLA2G2C (0.49) | USP2LPAR1LPAR3PLA2G2CSPHK1 | |
| SCHEMBL11348967 | 0.80 | GPR84 (0.53) | USP2LPAR1LPAR3PLA2G2CSPHK1 | |
| SCHEMBL14759111 | 0.79 | SPHK1 (0.51) | USP2LPAR1LPAR3PLA2G2CSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980670-A | Manufacture of methacrylic acid and butyrolactone | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | claimed |
| US-3980670-A | Manufacture of methacrylic acid and butyrolactone | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |