SCHEMBL9730284

SCHEMBL9730284

CCC(OC(C)C)C(C)O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20893308 0.88 TSHR (0.45) TSHRLMNA
SCHEMBL14895464 0.78 TDP1 (0.40) TSHR
SCHEMBL13770693 0.78 TDP1 (0.40) TSHR
SCHEMBL10181433 0.77 TSHR (0.36) TSHR
SCHEMBL9011656 0.77 TSHR (0.36) TSHR
SCHEMBL26767276 0.77 LMNA (0.33) TSHRLMNA
SCHEMBL139085 0.74
SCHEMBL16924994 0.74 TSHR (0.33) TSHRLMNA
SCHEMBL16782640 0.73 TSHR (0.47) TSHRLMNA
SCHEMBL9730228 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5167863-A Ferroelectricity; electrooptic switches HITACHI, LTD. (JP) 1992-12-01 US disclosed
EP-0322862-A2 Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators HITACHI, LTD. (JP) 1989-07-05 EP disclosed