SCHEMBL9730293

SCHEMBL9730293

CO/C=C(/C(=O)OC)n1cccc1C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9646097 1.00 ALDH1A1 (0.41) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9729795 1.00 ALDH1A1 (0.41) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9729803 0.89 MEN1 (0.43) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9329481 0.89 ALDH1A1 (0.43) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9329486 0.89 ALDH1A1 (0.43) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9329194 0.88 LMNA (0.42) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL9329187 0.88 LMNA (0.42) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL202895 0.86 KDM4E (0.31) ALDH1A1LMNAMAPT
SCHEMBL11256734 0.78 ALDH1A1 (0.49) ALDH1A1MEN1LMNAMAPTALOX12
SCHEMBL22074662 0.77 POLB (0.41) ALDH1A1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120755-A FUNGICIDAL SUBSTITUTED ACRYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1992-06-09 US disclosed
US-5091407-A HETEROCYCLIC COMPOUNDS AS FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-02-25 US disclosed