Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | TOP1 | P11387 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550416 | 0.84 | TSHR (0.75) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL30154503 | 0.82 | TSHR (1.00) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL640263 | 0.82 | TSHR (1.00) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL8830836 | 0.81 | TSHR (0.70) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL8350070 | 0.81 | TSHR (0.70) | TSHRRAB9AKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9650466 | 0.81 | TSHR (0.96) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL9489796 | 0.81 | TSHR (0.96) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL10697221 | 0.81 | TSHR (0.70) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL10541988 | 0.81 | TSHR (0.96) | TSHRRAB9AKDM4EALDH1A1GAA | |
| Silver SCHEMBL10541979 | 0.79 | TSHR (0.68) | TSHRRAB9AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112967-A | PROCESS FOR SYNTHESIZING ANTIBACTERIAL CEPHALOSPORIN COMPOUNDS | HOFFMANN-LA ROCHES INC. (US) | 1992-05-12 | — | — | US | claimed |
| EP-0453924-A1 | A process for synthesizing cephalosporin compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-30 | — | — | EP | claimed |