Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730369 | 0.78 | LMNA (0.39) | TP53 | |
| SCHEMBL566390 | 0.78 | LMNA (0.39) | TP53 | |
| SCHEMBL31369953 | 0.77 | SLC7A5 (0.46) | TSHRSLC7A5CYP2D6CYP2C19 | |
| SCHEMBL9731456 | 0.77 | CHRM1 (0.40) | TSHR | |
| Hydrochloric Acid SCHEMBL9730110 | 0.76 | LMNA (0.38) | TP53 | |
| SCHEMBL10593783 | 0.76 | SLC1A3 (0.43) | TSHRRNPEPSLC7A5MMP1MMP2 | |
| SCHEMBL18039277 | 0.75 | MMP1 (0.45) | TSHRRNPEPSLC7A5TP53MMP1 | |
| SCHEMBL4368789 | 0.75 | TSHR (0.38) | TSHRRNPEPSLC7A5TP53MMP1 | |
| SCHEMBL5718402 | 0.75 | MMP1 (0.45) | TSHRRNPEPSLC7A5TP53MMP1 | |
| SCHEMBL15290584 | 0.75 | TSHR (0.38) | TSHRRNPEPSLC7A5TP53MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |