Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372142 | 0.89 | GPR84 (0.60) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL1893849 | 0.89 | MEN1 (0.59) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL28177333 | 0.83 | GPR84 (0.53) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL368690 | 0.82 | GPR84 (0.59) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL29885154 | 0.82 | GPR84 (0.59) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL21535360 | 0.81 | GPR84 (0.57) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL29263805 | 0.81 | MEN1 (0.52) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL29263804 | 0.81 | MEN1 (0.52) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL7820062 | 0.79 | GPR84 (0.56) | GPR84FFAR1MAPTKDM4EAPAF1 | |
| SCHEMBL7573170 | 0.78 | MAPT (0.47) | GPR84FFAR1MAPTKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079258-A | Enzyme inhibitors, antiallergens treatment of asthma | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| CN-1040025-A | The preparation of new Tetrahydrobenzindolederivs propionic acid sulphonamide | BAYER AG (DE) | 1990-02-28 | — | — | CN | disclosed |