SCHEMBL368690

SCHEMBL368690

CC(C(=O)O)c1c[nH]c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.59
FFAR1 O14842 2/20 0.59
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
RECQL P46063 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
PKM P14618 1/20 0.56
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
HTR2B P41595 1/20 0.54
MGAM O43451 2/20 0.52
GAA P10253 2/20 0.52
SI P14410 2/20 0.52
MGAM2 Q2M2H8 2/20 0.52
NOD2 Q9HC29 1/20 0.52
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29885154 1.00 GPR84 (0.59) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL27514167 0.88 GPR84 (0.61) GPR84FFAR1MAPTKDM4EAPAF1
Triclofenol SCHEMBL9854793 0.85 MGAM (0.48) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL4001528 0.85 GPR84 (0.57) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL29053760 0.83 GPR84 (0.56) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL11372142 0.83 GPR84 (0.60) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL7820062 0.83 GPR84 (0.56) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL29182936 0.83 GPR84 (0.59) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL7047429 0.82 MEN1 (0.59) GPR84FFAR1MAPTKDM4EAPAF1
SCHEMBL3370820 0.82 MEN1 (0.59) GPR84FFAR1MAPTKDM4EAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234009-B Preparation method of nifedipine 合肥立方制药股份有限公司 2022-03-08 CN claimed
CN-113234009-A Preparation method of nifedipine 合肥立方制药股份有限公司 2021-08-10 CN claimed
CN-111253304-A Preparation method of nifedipine 合肥立方制药股份有限公司 2020-06-09 CN claimed
CN-111233672-A Method for synthesizing nifedipine intermediate by using combined catalyst 合肥立方制药股份有限公司 2020-06-05 CN claimed
WO-1999053930-A1 SYNTHETIC GLYCOAMINES AND METHODS FOR THEIR USE, ALONE OR IN COMBINATION WITH OTHER THERAPIES, THAT AFFECT CELL ADHESION, INHIBIT CANCER CELL GROWTH AND METASTASIS, AND INDUCE APOPTOSIS GLINSKII GUENNADI V (US) 1999-10-28 WO claimed
EP-0593559-A1 AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY MERCK SHARP & DOHME LTD. (GB) 1994-04-27 EP claimed
CN-119998926-A Polishing liquid for CMP, polishing liquid set for CMP and polishing method 株式会社力森诺科 2025-05-13 CN disclosed
WO-2025057339-A1 POLISHING LIQUID FOR CMP, POLISHING LIQUID SET FOR CMP, AND POLISHING METHOD 株式会社レゾナック 2025-03-20 WO disclosed
WO-2024078118-A1 CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2024-04-18 WO disclosed
WO-2023202652-A9 PHARMACEUTICAL COMBINATION AND USE THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-11-30 WO disclosed
WO-2023202652-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-10-26 WO disclosed
EP-4229029-A1 NOVEL GLUTAMINE ANALOGS Jacobio Pharmaceuticals Co., Ltd. (CN) 2023-08-23 EP disclosed
CN-115943147-A N-linked macrocyclic 7- (pyrazol-5-yl) -indole derivatives as MCL-1 inhibitors 詹森药业有限公司 2023-04-07 CN disclosed
WO-1996003377-A1 HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS SANKYO COMPANY, LIMITED (JP) 1996-02-08 WO disclosed
EP-0642513-A1 INDOLOCARBAZOLE IMIDES AND THEIR USE GÖDECKE AKTIENGESELLSCHAFT (DE) 1995-03-15 EP disclosed
EP-0593559-A1 AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY MERCK SHARP & DOHME LTD. (GB) 1994-04-27 EP disclosed
WO-1993024491-A1 INDOLOCARBAZOLE IMIDES AND THEIR USE Gödecke Aktiengesellschaft (DE) 1993-12-09 WO disclosed
EP-0384349-A1 Substituted pyrroles F. HOFFMANN-LA ROCHE AG (CH) 1990-08-29 EP disclosed
US-4808728-A Production of indolepyruvic acid and the 5-hydroxy derivative thereof POLIFARMA S.P.A. (IT) 1989-02-28 US disclosed
EP-0068563-A2 Heterocyclic acetic acid compounds and compositions for treating bone diseases THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP disclosed