Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520236 | 0.87 | MAPT (0.33) | ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL7889687 | 0.86 | MAPT (0.41) | MAPTSMN1; SMN2 | |
| SCHEMBL10623749 | 0.86 | ALDH1A1 (0.30) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5402910 | 0.81 | — | — | |
| SCHEMBL7888958 | 0.80 | — | — | |
| SCHEMBL9874454 | 0.80 | ATM (0.39) | ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL10420155 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL9731340 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL10417426 | 0.78 | PPOX (0.43) | ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10419659 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136868-A | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-4868321-A | FOR HERBICIDES | FMC CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0252982-A4 | HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0252982-A1 | HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1988-01-20 | — | — | EP | disclosed |
| WO-1987003873-A1 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1987-07-02 | — | — | WO | disclosed |