Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158993 | 0.95 | SMN1; SMN2 (0.93) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9418627 | 0.85 | TSHR (0.73) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9418611 | 0.79 | HTT (0.61) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1310082 | 0.77 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11873039 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8973821 | 0.77 | HTT (0.63) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1391802 | 0.75 | MEN1 (1.00) | SMN1; SMN2MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL8277453 | 0.74 | MAPK1 (0.73) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10970203 | 0.74 | ALDH1A1 (0.63) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10970031 | 0.73 | ALDH1A1 (0.58) | SMN1; SMN2MAPK1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099017-A | N,N'-BIS-1,3,5-TRIAZIN-6-YLPIPERAZINES, AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| EP-0413999-A2 | N,N-bis-1,3,5-triazine-6-yl-piperazines and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |