Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122441 | 0.98 | MAPT (0.43) | MAPTHTTCYP3A4TSHRRECQL | |
| SCHEMBL8283700 | 0.82 | CYP3A4 (0.43) | MAPTHTTCYP3A4TSHRRECQL | |
| Succinimide SCHEMBL11622603 | 0.82 | MEN1 (0.39) | MAPTHTTCYP3A4TSHRRECQL | |
| SCHEMBL8414964 | 0.79 | MAPT (0.47) | MAPTHTTCYP3A4TSHRCYP1A2 | |
| SCHEMBL28261577 | 0.79 | TAAR1 (0.42) | MAPTHTTCYP3A4TSHRRECQL | |
| SCHEMBL9311053 | 0.79 | TRPV1 (0.42) | MAPTHTTCYP3A4TSHRRECQL | |
| SCHEMBL10310076 | 0.79 | MAPT (0.40) | MAPTHTTCYP3A4RECQLCYP1A2 | |
| SCHEMBL11519753 | 0.78 | ENPP1 (0.44) | MAPTHTTKMT2AADRA2C | |
| SCHEMBL28226301 | 0.78 | ADRA2C (0.51) | MAPTHTTCYP3A4TSHRCYP1A2 | |
| SCHEMBL10540382 | 0.78 | KCNH2 (0.43) | MAPTCYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116958-A | Containing releasable oxime or lactam group | CIBA-GEIGY CORPORATION (US) | 1992-05-26 | — | — | US | disclosed |