Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938171 | 0.86 | MAPT (0.41) | MAPTHTTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL12203602 | 0.83 | TSHR (0.39) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10561697 | 0.81 | MAPT (0.39) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL21257666 | 0.81 | AOC1 (0.44) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL19122441 | 0.81 | MAPT (0.43) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL24947728 | 0.81 | TAAR1 (0.39) | HTTALDH1A1KDM4EPOLBNPSR1 | |
| SCHEMBL19006788 | 0.80 | KCNH2 (0.40) | MAPTHTTPTGS2ALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL9730743 | 0.79 | MAPT (0.42) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9065360 | 0.79 | MAPT (0.40) | MAPTHTTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL5436495 | 0.78 | KCNH2 (0.46) | MAPTCYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3025584-B1 | PLANT DISEASE CONTROL COMPOSITION AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | MAPT 3490/4885HTT 4421/4885CYP3A4 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.