Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | GABRP | O00591 | 5/20 | 0.39 |
| ▸ | GABRD | O14764 | 5/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.39 |
| ▸ | GABRE | P78334 | 5/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339152 | 0.96 | GAA (0.43) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10441625 | 0.90 | GAA (0.38) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9730621 | 0.85 | CYP3A4 (0.47) | GAAGABRB3SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL10444468 | 0.85 | CYP3A4 (0.45) | GAASMN1; SMN2LMNACYP3A4ALDH1A1 | |
| SCHEMBL10676858 | 0.79 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9730810 | 0.78 | GABRB3 (0.37) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9581399 | 0.78 | GABRB3 (0.35) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9681975 | 0.77 | GAA (0.41) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9582286 | 0.76 | GABRA2 (0.38) | GAAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9582428 | 0.75 | GAA (0.40) | GAAGABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |