Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431491 | 0.82 | ERN1 (0.47) | ERN1KDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29950678 | 0.82 | ERN1 (0.47) | ERN1KDM4ESMN1; SMN2ALDH1A1TDP1 | |
| Formamide SCHEMBL9731196 | 0.81 | ESR2 (0.34) | ESR1ESR2ESRRBESRRAERN1 | |
| Formamide SCHEMBL9731521 | 0.75 | MYC (0.39) | ERN1ELANEKDM4ESMN1; SMN2ALDH1A1 | |
| Formamide SCHEMBL9732527 | 0.74 | NQO2 (0.47) | ESR1ESR2ESRRBESRRAERN1 | |
| Formamide SCHEMBL9732590 | 0.73 | TRPM4 (0.35) | ERN1KDM4EALDH1A1GLAHPGD | |
| Formamide SCHEMBL9732252 | 0.73 | ALDH1A1 (0.40) | KDM4ESMN1; SMN2ALDH1A1GLAHPGD | |
| Formamide SCHEMBL9731411 | 0.73 | ERN1 (0.44) | ESR1ESR2ESRRBESRRAERN1 | |
| SCHEMBL9730827 | 0.73 | POLB (0.45) | ERN1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| Formamide SCHEMBL9724278 | 0.72 | PTPN22 (0.46) | ERN1KDM4EALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |