Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950812 | 0.82 | ERN1 (0.42) | ERN1 | |
| Formamide SCHEMBL9730831 | 0.81 | ESR1 (0.40) | ESR2ESRRBESR1ESRRAERN1 | |
| Formamide SCHEMBL9731574 | 0.76 | PLAU (0.35) | ERN1CYP1A2 | |
| Formamide SCHEMBL9731154 | 0.74 | MAPT (0.48) | ERN1CYP1A2 | |
| Formamide SCHEMBL9731767 | 0.73 | ERN1 (0.39) | ESR2ESRRBESR1ESRRASLC9A1 | |
| SCHEMBL9731192 | 0.73 | EGFR (0.42) | ERN1 | |
| Formamide SCHEMBL9730999 | 0.72 | CYP1A2 (0.37) | ERN1CYP1A2 | |
| SCHEMBL2145695 | 0.71 | ALDH1A1 (0.47) | CYP1A2 | |
| SCHEMBL9318064 | 0.71 | ALDH1A1 (0.41) | ESR2ESRRBESR1ESRRACYP1A2 | |
| SCHEMBL9731190 | 0.70 | NQO2 (0.32) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |