Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731471 | 0.88 | KDM4E (0.69) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| SCHEMBL21625616 | 0.82 | KDM4E (0.75) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| Formamide SCHEMBL9731341 | 0.82 | KDM4E (0.42) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| SCHEMBL7258719 | 0.79 | KDM4E (0.70) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| SCHEMBL28200686 | 0.78 | KDM4E (0.68) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| SCHEMBL28677018 | 0.78 | KDM4E (0.68) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| Formamide SCHEMBL9730953 | 0.76 | ERN1 (0.36) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| Formamide SCHEMBL9731188 | 0.76 | KDM4E (0.56) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| SCHEMBL6538538 | 0.76 | PARP1 (0.45) | KDM4EL3MBTL1RAB9AHSP90AA1IDO1 | |
| Formamide SCHEMBL9732633 | 0.74 | MAPT (0.49) | KDM4EL3MBTL1RAB9AHSP90AA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |