Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304325 | 0.91 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Formamide SCHEMBL9731154 | 0.88 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29935774 | 0.80 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL333756 | 0.80 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Formamide SCHEMBL9731312 | 0.79 | ESR2 (0.47) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1239664 | 0.78 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL27593140 | 0.78 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL27545773 | 0.78 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Pyrazole SCHEMBL28116200 | 0.78 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Formamide SCHEMBL9730946 | 0.78 | TLR8 (0.40) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |