Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841924 | 0.83 | MAPT (0.62) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL9141569 | 0.83 | MAPT (0.55) | MAPTHCAR3L3MBTL1 | |
| SCHEMBL9730406 | 0.83 | MAPT (0.55) | MAPTHCAR3L3MBTL1 | |
| SCHEMBL9145319 | 0.80 | MAPT (0.67) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL796493 | 0.78 | MAPT (1.00) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL841827 | 0.78 | MAPT (0.68) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL15477238 | 0.77 | L3MBTL1 (0.57) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL840140 | 0.77 | MAPT (0.62) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL24774417 | 0.77 | MAPT (0.57) | MAPTHCAR3L3MBTL1HCAR2P4HA1 | |
| SCHEMBL7560975 | 0.77 | MAPT (0.61) | MAPTHCAR3L3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145601-A | Ferroelectric liquid crystals with nicotinic acid cores | THE UNIVERSITY OF COLORADO FOUNDATION INC. (US) | 1992-09-08 | — | — | US | disclosed |