Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141569 | 1.00 | MAPT (0.55) | MAPTHCAR3TP53TSHRALDH1A1 | |
| SCHEMBL9730464 | 0.88 | MAPT (0.40) | MAPTHCAR3TP53TSHRALDH1A1 | |
| SCHEMBL9730460 | 0.88 | MAPT (0.40) | MAPTHCAR3TP53TSHRALDH1A1 | |
| SCHEMBL9730910 | 0.83 | MAPT (0.64) | MAPTHCAR3L3MBTL1 | |
| SCHEMBL9730402 | 0.81 | MAPT (0.57) | MAPTTP53TSHRALDH1A1PLA2G4B | |
| SCHEMBL9730675 | 0.81 | MAPT (0.57) | MAPTTP53TSHRALDH1A1PLA2G4B | |
| SCHEMBL6946501 | 0.80 | MAPT (0.69) | MAPTHCAR3TP53TSHRPLA2G4B | |
| SCHEMBL4276906 | 0.80 | MAPT (0.69) | MAPTHCAR3TP53TSHRPLA2G4B | |
| SCHEMBL14125959 | 0.80 | MAPT (0.69) | MAPTHCAR3TP53TSHRPLA2G4B | |
| SCHEMBL9578575 | 0.80 | MAPT (0.69) | MAPTHCAR3TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145601-A | Ferroelectric liquid crystals with nicotinic acid cores | THE UNIVERSITY OF COLORADO FOUNDATION INC. (US) | 1992-09-08 | — | — | US | disclosed |