Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 6/20 | 0.61 |
| ▸ | MME | P08473 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.50 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.50 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294222 | 0.92 | NAALAD2 (0.53) | NAALAD2MMEGAA | |
| SCHEMBL31294614 | 0.92 | NAALAD2 (0.53) | NAALAD2MMEGAA | |
| SCHEMBL5283204 | 0.88 | KMT2A (0.56) | NAALAD2MMEACE | |
| SCHEMBL18493709 | 0.86 | MME (0.56) | MMEACE | |
| SCHEMBL7374278 | 0.86 | MME (0.71) | MME | |
| SCHEMBL28885066 | 0.84 | GPR88 (0.48) | NAALAD2GAA | |
| SCHEMBL6138235 | 0.83 | MME (0.56) | MME | |
| SCHEMBL2325127 | 0.82 | LTA4H (0.56) | MME | |
| SCHEMBL2325133 | 0.82 | LTA4H (0.56) | MME | |
| SCHEMBL2323705 | 0.81 | MME (0.54) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162333-A | Treating transplantation rejection, autoimmune diseases, antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |