Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959175 | 0.77 | CA2 (0.63) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL4402699 | 0.77 | GPR55 (0.55) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL9646002 | 0.77 | CA2 (0.57) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL448549 | 0.76 | CA2 (0.61) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL8959195 | 0.76 | CA2 (0.61) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL17733082 | 0.76 | CA2 (0.61) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL9731510 | 0.76 | GAA (0.57) | CA2CA1MAPTALDH1A1GAA | |
| SCHEMBL8959243 | 0.74 | CA2 (0.59) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL9648998 | 0.74 | CA2 (0.53) | CA2CA1ALOX15MAPTHPN | |
| SCHEMBL4398454 | 0.73 | CA2 (0.49) | CA2CA1ALOX15MAPTHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102897-A | Antiinflammatory, antiarthritic, antiulcer or antiischemic agents | WARNER-LAMBERT COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0449211-A1 | 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues | WARNER-LAMBERT COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |