Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731449 | 0.79 | ALDH1A1 (0.44) | IKBKBALDH1A1MAPTHPGDGLA | |
| SCHEMBL9730851 | 0.78 | MEN1 (0.49) | ALDH1A1MAPTKDM4EGAARAB9A | |
| SCHEMBL9730823 | 0.75 | AKR1C3 (0.39) | KDM4EHTTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL9732739 | 0.73 | MGAM (0.51) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL9731547 | 0.73 | MGAM (0.55) | ALDH1A1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9665736 | 0.72 | IKBKB (0.53) | IKBKBALDH1A1MAPTHPGDGLA | |
| SCHEMBL352221 | 0.72 | IKBKB (0.51) | IKBKBALDH1A1MAPTHPGDGLA | |
| SCHEMBL31133499 | 0.72 | IKBKB (0.51) | IKBKBALDH1A1MAPTHPGDGLA | |
| SCHEMBL9732515 | 0.71 | CDC25B (0.48) | ALDH1A1MAPTHPGDGLAKDM4E | |
| SCHEMBL14915531 | 0.70 | ALDH1A1 (0.54) | IKBKBALDH1A1MAPTHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |