Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731190 | 0.82 | NQO2 (0.32) | AKR1C3AKR1C2AKR1C1KDM4ELMNA | |
| SCHEMBL9731511 | 0.77 | MYC (0.37) | KDM4ELMNAPOLBERN1HTT | |
| SCHEMBL9732515 | 0.76 | CDC25B (0.48) | KDM4ELMNAPOLBERN1HTT | |
| SCHEMBL9732624 | 0.76 | PTPN1 (0.46) | KDM4ESMN1; SMN2LMNAPOLBERN1 | |
| SCHEMBL9732242 | 0.75 | IKBKB (0.40) | KDM4ESMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL9732583 | 0.75 | ERN1 (0.33) | KDM4ELMNAPOLBERN1HTT | |
| SCHEMBL9731401 | 0.74 | ERN1 (0.39) | KDM4EPOLBERN1USP2L3MBTL1 | |
| SCHEMBL662652 | 0.74 | KDM4E (0.64) | AKR1C3AKR1C2AKR1C1KDM4ESMN1; SMN2 | |
| SCHEMBL30172583 | 0.74 | KDM4E (0.64) | AKR1C3AKR1C2AKR1C1KDM4ESMN1; SMN2 | |
| SCHEMBL9731137 | 0.74 | THRB (0.41) | KDM4ELMNAPOLBERN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |