Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731312 | 0.89 | ESR2 (0.47) | ESR2ESR1MAPTMEN1KMT2A | |
| SCHEMBL8764571 | 0.82 | CCR1 (0.53) | TLR8ESR2ESR1MAPTMEN1 | |
| Formamide SCHEMBL9731411 | 0.81 | ERN1 (0.44) | ESR2ESR1MAPTMEN1KMT2A | |
| Formamide SCHEMBL9732633 | 0.78 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9730944 | 0.74 | MAPT (0.55) | TLR8ESR2ESR1MAPTMEN1 | |
| Formamide SCHEMBL9730985 | 0.73 | MEN1 (0.35) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9730941 | 0.71 | MAPT (0.40) | TLR8ESR2ESR1MAPTMEN1 | |
| SCHEMBL29956482 | 0.70 | CCR1 (0.50) | ESR2ESR1MAPTMEN1KMT2A | |
| Formamide SCHEMBL9731154 | 0.70 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1HPGD | |
| Formamide SCHEMBL9730953 | 0.70 | ERN1 (0.36) | ESR2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |