Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120605 | 0.83 | ALDH1A1 (0.37) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL344147 | 0.82 | MAPT (0.36) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL29047178 | 0.81 | MAPT (0.35) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL27740138 | 0.81 | MAPT (0.35) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL180233 | 0.81 | MAPT (0.35) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL29119739 | 0.80 | KMT2A (0.36) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL29119762 | 0.78 | ELANE (0.35) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL8166860 | 0.77 | MAPT (0.39) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL29429342 | 0.77 | L3MBTL1 (0.40) | MAPTKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL28441977 | 0.76 | ELANE (0.36) | MAPTKDM4EHSD17B10MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098445-A | Halotriazine reactive compounds for bonding with polymers for radiation resistance | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-4929250-A | HALOTRIAZINE DERIVATIVES, QUARTERINARY AMMONIUM SALTS | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |