Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080508 | 0.79 | CACNA1F (0.62) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL9628026 | 0.79 | KCNH2 (0.76) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL9080505 | 0.76 | KCNH2 (0.59) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL11528815 | 0.76 | ABCC1 (0.58) | LMNAHTTABCC1 | |
| SCHEMBL10532863 | 0.73 | HPGD (0.58) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL9628220 | 0.73 | HPGD (0.58) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL9826819 | 0.72 | KCNH2 (0.67) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL7847086 | 0.72 | HPGD (0.66) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL9624965 | 0.72 | HPGD (0.56) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL6014610 | 0.71 | HPGD (1.00) | KDM4EHPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006080-A1 | ANTIARRHYTHMIC AGENTS | PFIZER LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |