Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.53 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.53 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.53 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733181 | 0.79 | KMT2A (0.48) | HTR2AKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL5947960 | 0.78 | HTR2A (0.69) | HTR2AKMT2ATRPV1 | |
| SCHEMBL10382030 | 0.76 | TRPV1 (0.52) | HTR2AKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9583723 | 0.76 | MEN1 (0.46) | KMT2AKDM4EMEN1SSTR1SSTR2 | |
| SCHEMBL14036722 | 0.76 | HTR2A (0.75) | HTR2AKDM4EGPR84 | |
| SCHEMBL9733190 | 0.74 | PLA2G2A (0.60) | KMT2AKDM4EMEN1ALDH1A1MITF | |
| SCHEMBL2539047 | 0.74 | HTR2A (0.67) | HTR2AKMT2A | |
| SCHEMBL2538776 | 0.74 | HTR2A (0.67) | HTR2AKMT2AMEN1 | |
| SCHEMBL5947303 | 0.74 | HTR2A (0.78) | HTR2AKMT2A | |
| SCHEMBL948317 | 0.74 | HTR2A (1.00) | HTR2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |