Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 6/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9733235 | 0.99 | PLA2G2A (0.59) | PLA2G2AHTR6ADRB2MTNR1AMTNR1B | |
| SCHEMBL9732645 | 0.91 | PLA2G2A (0.61) | PLA2G2AHTR6ADRB2MTNR1AMTNR1B | |
| SCHEMBL9732261 | 0.90 | ICMT (0.56) | PLA2G2AHTR6ADRB2MTNR1AMTNR1B | |
| SCHEMBL9733098 | 0.89 | ICMT (0.50) | PLA2G2AADRB2ICMTPPARGPPARD | |
| SCHEMBL9732896 | 0.88 | PLA2G2A (0.69) | PLA2G2AHTR6MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9731969 | 0.87 | ICMT (0.50) | PLA2G2AADRB2ICMTKDM4EMEN1 | |
| SCHEMBL9731962 | 0.86 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BICMT | |
| SCHEMBL9733236 | 0.85 | HTR6 (0.50) | HTR6ICMTKMT2AALDH1A1LMNA | |
| SCHEMBL9733129 | 0.85 | PLA2G2A (0.66) | PLA2G2AHTR6MTNR1AMTNR1BKDM4E | |
| SCHEMBL9732518 | 0.85 | ICMT (0.48) | PLA2G2AHTR6ADRB2ICMTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | claimed |
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |